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Controlling Blood Sugar Peaks: Early Time-Restricted Feeding

In a crossover study involving 10 adults with prediabetes, restricting eating to an 8 AM-4 PM time window for 6 days resulted in a decrease in the average amplitude of glycemic excursions by 0.5 mmol/L (approximately 9 mg/dL) compared to a more typical feeding schedule. This study demonstrates that limiting food intake to the resting period can enhance running performance. Previous research has shown that restricting eating to a window of six to 12 hours during the daytime, without necessarily changing the type or quantity of food consumed, can lead to improved weight loss, reduced spikes in blood sugar levels, and lower blood pressure. Controlling Blood Sugar Peaks: Early Time-Restricted Feeding.

Conducted by researchers at NYU Lang one Health, the study involved 10 patients with prediabetes and obesity. The participants were adults between 18 and 75 years old (average age: 58 years old) with prediabetes (average A1c: 5.8%) and a body mass index above 28 kg/m2 (average: 37). Dietary interventions to combat obesity have gained significant attention in recent years. However, Min-Dian Li from the Army Medical University in China suggests that nighttime eating could also offer benefits.

Optimizing Performance and Health: The Benefits of Early Time-Restricted Feeding

The researchers discovered that early time-restricted feeding (eTRF), a form of intermittent fasting that involves consuming 80% of daily calorie intake within the first 6-8 hours of the day, had a positive impact on blood parameters. Participants adhered to a calorie-specific diet with early time-restricted feeding for 7 days, consuming meals at 8:00 AM, 11:00 AM, and 2:00 PM, with 80% of their daily calorie intake before 1:00 PM.

Controlling Blood Sugar Peaks

It is worth noting that intermittent fasting, which restricts eating to a few hours each day, has better compliance and retains key metabolic benefits compared to caloric restriction. Earlier studies have shown that mice that eat only during the day, when they typically rest unlike humans, are at a higher risk of developing diabetes and accumulating fat in their livers, unlike mice that eat at any time.

Enhancing Metabolic Control: The Impact of Early Time-Restricted Feeding on Blood Glucose Peaks

Prediabetes refers to a condition in which an individual has higher than normal blood sugar levels but not high enough to be diagnosed as full or overt diabetes. During a second 7-day study period, participants followed a “usual feeding” schedule, consuming meals at 8:00 AM, 1:00 PM, and 6:00 PM, with 50% of their daily calorie intake occurring after 4:00 PM. However, Li and his colleagues have now found evidence that mice that eat during their resting hours, equivalent to our nighttime, may perform better in exercise endurance tests. In Kenya, the estimated prevalence of diabetes is approximately 3.3%.

In the study, researchers used a crossover design and randomly assigned subjects to different eating protocols. Subjects followed an isocaloric diet designed to maintain their weight throughout the study. The concept of intermittent fasting stems from mouse studies that have demonstrated the improvement of metabolic homeostasis in obesity induced by high-fat diets.

Promoting Stable Blood Sugar Levels: Exploring the Effects of Early Time-Restricted Feeding

Li states, “If we expose mice to this schedule for a short period, it positively impacts their running performance.” Several approaches can help reduce blood sugar levels and potentially prevent the development of overt diabetes, including maintaining a moderate weight and engaging in regular exercise. This new research highlights another potential strategy: early time-restricted feeding.

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